Twenty-four hour pattern in symptom intensity of viral and allergic rhinitis: Treatment implications
Identifieur interne : 001A37 ( Main/Exploration ); précédent : 001A36; suivant : 001A38Twenty-four hour pattern in symptom intensity of viral and allergic rhinitis: Treatment implications
Auteurs : Michael H. Smolensky [Canada] ; Alain Reinberg [Canada] ; Gaston Labrecque [Canada]Source :
- The Journal of Allergy and Clinical Immunology [ 0091-6749 ] ; 1995.
English descriptors
- KwdEn :
- Teeft :
- Activity period, Activity span, Administration time, Adult patients, Aerosol corticosteroids, Airway, Airway resistance, Alertness, Allergic, Allergic asthma, Allergic rhinitis, Allergy, Allergy clin immunol, Allergyclin, Allergyclin immunol, Antihistamine, Antihistamine effect, Antitussive effect, Arachidonic acid, Arbitrary units, Asthma, Baseline, Biochemical interactions, Biological rhythms, Breakfast time, Chronobiol intern, Chronopharmacology, Chronotherapy, Circadian, Circadian changes, Circadian patterns, Circadian rhythm, Circadian rhythmicity, Circadian rhythms, Circadian time structure, Circadian variation, Circadian variations, Clin, Clin pharmacol, Clock time, Cold virus, Corona virus, Corticosteroid, Cosine curve, Cosinor analysis, Cough frequency, Daily activity, Daily dose, Data collection, Dekker, Difficult time, Dinner time, Disease processes, Diurnal activity, Diurnal variation, Diurnally, Double amplitude, Dynamic lung compliance, Early evening, Edematous response, Evening administration, Gastrointestinal tract, Healthy children, Immunol, Infectious disease, Influenza, Influenza sufferers, Influenza viruses, Initial hours, Ipratropium bromide, Itchy eyes, Itchy nose, Laboratory medicine, Labrecque, Local midnight, Lung function, Main symptom, Marcel, Marcel dekker, Medical history, Medication, Mental alertness, Mequitazine, Morning symptoms, Nasal, Nasal allergy, Nasal congestion, Nasal symptoms, Natural colds, Nocturnal asthma, Other organs, Peak effect, Perennial rhinitis, Prominent patterns, Prominent variation, Pulmonary function, Regimen, Reinberg, Rheumatoid arthritis, Rhinitis, Rhinorrhea, Runny nose, Seasonal rhinitis, Severe symptom, Smolensky, Standard error, Stuffy nose, Sublingual temperature, Sufferer, Symptom, Symptom intensity, Symptomatic days, Temporal variation, Time clock hours, Topical corticosteroid aerosols, Topical corticosteroids, Troublesome symptom, Troublesome symptoms, Ulcer disease, Upper airways, Vagal tone, Viral, Viral infection, Viral rhinorrhea, Visual analog scales, Young adults.
Abstract
Abstract: The symptoms of rhinorrhea secondary to influenza and cold virus or seasonal and perennial allergic rhinitis are circadian rhythmic. Cough frequency and handkerchief use by persons suffering from virus-induced rhinorrhea are more prominent during the daytime, especially during the initial hours after awakening from nocturnal sleep. The elevation in sublingual temperature as well as the decrement in mental alertness associated with influenza in particular are more profound at this time. Sneezing, blocked nose, and runny nose secondary to allergic rhinitis are also greater in intensity during the morning in approximately 70% of sufferers. The day-night variation in symptom intensity amounts to approximately 20% of the 24-hour mean level. The treatment of these diseases and their symptoms has traditionally involved equal-interval, equal-dose (homeostatic) medication schedules. The effects of antihistamine and antiinflammatory medicines may be enhanced by timing them to the day-night temporal pattern in symptom manifestation and intensity to achieve an optimization of their beneficial effects with control of toxicity, that is, as a chronotherapy. (J ALLERGY CLIN IMMUNOL 1995;95:1084-96.)
Url:
DOI: 10.1016/S0091-6749(95)70212-1
Affiliations:
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Cough frequency and handkerchief use by persons suffering from virus-induced rhinorrhea are more prominent during the daytime, especially during the initial hours after awakening from nocturnal sleep. The elevation in sublingual temperature as well as the decrement in mental alertness associated with influenza in particular are more profound at this time. Sneezing, blocked nose, and runny nose secondary to allergic rhinitis are also greater in intensity during the morning in approximately 70% of sufferers. The day-night variation in symptom intensity amounts to approximately 20% of the 24-hour mean level. The treatment of these diseases and their symptoms has traditionally involved equal-interval, equal-dose (homeostatic) medication schedules. The effects of antihistamine and antiinflammatory medicines may be enhanced by timing them to the day-night temporal pattern in symptom manifestation and intensity to achieve an optimization of their beneficial effects with control of toxicity, that is, as a chronotherapy. (J ALLERGY CLIN IMMUNOL 1995;95:1084-96.)</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Smolensky, Michael H" sort="Smolensky, Michael H" uniqKey="Smolensky M" first="Michael H." last="Smolensky">Michael H. Smolensky</name></noRegion><name sortKey="Labrecque, Gaston" sort="Labrecque, Gaston" uniqKey="Labrecque G" first="Gaston" last="Labrecque">Gaston Labrecque</name><name sortKey="Reinberg, Alain" sort="Reinberg, Alain" uniqKey="Reinberg A" first="Alain" last="Reinberg">Alain Reinberg</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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